Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study.

@article{Pfhler2003TreosulfanAG,
  title={Treosulfan and gemcitabine in metastatic uveal melanoma patients: results of a multicenter feasibility study.},
  author={Claudia Pf{\"o}hler and Ian A Cree and Selma Ugurel and Christoph Kuwert and Nikolas K. Haass and Karsten Neuber and Ulrich R Hengge and Pippa G. Corrie and Markus Zutt and Wolfgang Tilgen and Uwe Reinhold},
  journal={Anti-cancer drugs},
  year={2003},
  volume={14 5},
  pages={337-40}
}
No effective treatment currently exists for metastatic uveal melanoma. However, recent results obtained by an ATP-based tumor chemosensitivity assay have shown consistent activity of treosulfan+gemcitabine in up to 80% of tumor specimens tested. In this study we describe the first clinical results observed with this drug combination at different European centers in patients with metastatic uveal melanoma. Clinical case series of patients with metastatic uveal melanoma were treated with… CONTINUE READING
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