Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.

@article{Hidalgo2011TrendsTL,
  title={Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.},
  author={{\'A}lvaro L. Lagomasino Hidalgo and Ana Mar{\'i}a Cuadros Carvajal and Birte Vester and M. Jodeane Pringle and Germ{\'a}n Naharro and P. Talavera Rubio},
  journal={Antimicrobial agents and chemotherapy},
  year={2011},
  volume={55 7},
  pages={
          3330-7
        }
}
The antimicrobial susceptibility of clinical isolates of Brachyspira hyodysenteriae in Spain was monitored, and the underlying molecular mechanisms of resistance were investigated. MICs of tylosin, tiamulin, valnemulin, lincomycin, and tylvalosin were determined for 87 B. hyodysenteriae isolates recovered from 2008 to 2009 by broth dilution. Domain V of the 23S rRNA gene and the ribosomal protein L3 gene were sequenced in 20 isolates for which the tiamulin MIC was ≥ 4 μg/ml, presenting… CONTINUE READING

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