Trends in the incidence of hepatocellular carcinoma in boys and girls in Taiwan after large-scale hepatitis B vaccination.


In July 1984, large-scale hepatitis B vaccination of newborns began in Taiwan. Vaccination decreased the overall incidence of childhood hepatocellular carcinoma (HCC). We conducted this study to learn whether the vaccination program had the same effect on boys and girls. We collected liver carcinoma (including HCC and hepatoblastoma) deaths from 1974 to… (More)