Trends in template/fragment-free protein structure prediction

  title={Trends in template/fragment-free protein structure prediction},
  author={Yaoqi Zhou and Yong Duan and Yuedong Yang and Eshel Faraggi and Hongxing Lei},
  booktitle={Theoretical chemistry accounts},
Predicting the structure of a protein from its amino acid sequence is a long-standing unsolved problem in computational biology. Its solution would be of both fundamental and practical importance as the gap between the number of known sequences and the number of experimentally solved structures widens rapidly. Currently, the most successful approaches are based on fragment/template reassembly. Lacking progress in template-free structure prediction calls for novel ideas and approaches. This… CONTINUE READING

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