Trends in beta-lactam resistance among Enterobacteriaceae.

  title={Trends in beta-lactam resistance among Enterobacteriaceae.},
  author={Patrice L. Nordmann},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={27 Suppl 1},
beta-Lactam resistance among Enterobacteriaceae is related primarily to the emergence of novel beta-lactamases. The class A extended-spectrum beta-lactamases hydrolyze extended-spectrum beta-lactams and are inhibited by clavulanic acid. These beta-lactamases are divided in two groups: TEM and SHV derivatives and non-TEM and non-SHV extended-spectrum beta-lactamases (CTX-M1, CTX-M2, MEN-1, PER-1, PER-2, TOHO-1, and VEB-1). The plasmid-mediated cephalosporinases (MIR-1, FOX-1, MOX-1, BIL-1, CMY-1… CONTINUE READING
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