Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a metropolitan Detroit health system.

@article{Reddy2010TrendsIA,
  title={Trends in antimicrobial resistance of Acinetobacter baumannii isolates from a metropolitan Detroit health system.},
  author={T Raghavendar Reddy and Teena Chopra and Dror Marchaim and Jason M. Pogue and George John Alangaden and Hossein Salimnia and Dina A. Boikov and Shiri Navon-Venezia and Robert Akins and Philip Selman and Sorabh Dhar and Keith S. Kaye},
  journal={Antimicrobial agents and chemotherapy},
  year={2010},
  volume={54 5},
  pages={2235-8}
}
A phenotypic and genotypic analysis of Acinetobacter baumannii was conducted from 2003 to 2008 in Detroit, MI. The incidence of A. baumannii increased from 1.7 to 3.7/1,000 patient days during the study period. Susceptibility to ampicillin-sulbactam and imipenem decreased from approximately 90% to approximately 40%. Genotyping revealed polyclonality, suggesting either emergence of multiple resistant strains or spread of a common genetic element. The sharp rise mandates major multidisciplinary… CONTINUE READING