Trends in Particle Formation of Bioactive Compounds Using Supercritical Fluids and Nanoemulsions

  title={Trends in Particle Formation of Bioactive Compounds Using Supercritical Fluids and Nanoemulsions},
  author={M. Thereza and Maria Thereza de Moraes Santos Gomes and Diego Santos and M. Angela and Angela M.A Meireles},
  journal={Food and Public Health},
This review discusses the recent developments in the application of supercritical fluid technologies for the production of composites or encapsulates of bioactive compounds. Various supercritical particle formation technologies are briefly described, including processes in which the supercritical fluid acts as a solute, solvent, and antisolvent. The main features and mechanisms of antisolvent techniques that contribute to the understanding of the fundamentals of the Supercritical Fluid… 

Figures and Tables from this paper

Application of Supercritical Fluids in the Conservation of Bioactive Compounds: A Review
The precipitation from supercritical antisolvents (SASs) of natural compounds solutions has become an excellent alternative to improve the solubility and availability of poorly water-soluble
Encapsulation of Food Compounds Using Supercritical Technologies: Applications of Supercritical Carbon Dioxide as an Antisolvent
The application of supercritical technologies as an alternative to conventional methods for encapsulating food compounds is an area of research that can lead to significant innovations in various
Modern supercritical fluid technology for food applications.
  • J. King
  • Chemistry, Medicine
    Annual review of food science and technology
  • 2014
The use of the solubility parameter theory (SPT) for rationalizing the results obtained when employing sub- and supercritical media to food and nutrient-bearing materials and for optimizing processing conditions is advocated.
High Yield and High Loading Preparation of Curcumin-PLGA Nanoparticles Using a Modified Supercritical Antisolvent Technique
A modified supercritical antisolvent method, aiming at high yielding and high loading, is developed for preparation of drug-loaded polymeric nanoparticles and the maximum yield of theCurcumin–PLGA nanoparticles 50 nm in size and the curcumin loading in it reach 96% and 45%, respectively.
Supercritical Technology Applied to the Production of Bioactive Compounds: Research Studies Conducted at LASEFI from 2009 to 2013
This paper presents a review of the scientific research studies conducted in the period from 2009 to 2013 at LASEFI (Laboratory of Supercritical Technology: Extraction, Fractionation and


Fine particle formation using supercritical fluids
Micronization of drug particles via RESS process
Recent developments in particle design using supercritical fluids
Formation of polymer particles with supercritical fluids: A review