Trends in Epidemiology and Microbiology of Severe Sepsis and Septic Shock in Children.

  title={Trends in Epidemiology and Microbiology of Severe Sepsis and Septic Shock in Children.},
  author={Mukul Sehgal and Hugh Ladd and Balagangadhar R. Totapally},
  journal={Hospital pediatrics},
BACKGROUND AND OBJECTIVES To explore the microbiologic etiology and trends in incidence and survival of nonneonatal pediatric sepsis in the United States by using the 2006, 2009, and 2012 Kids' Inpatient Database. METHODS Children with sepsis were identified by using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for severe sepsis and septic shock (ICD-9-CM cohort) and by the modified Angus method, which incorporates ICD-9-CM codes for… Expand
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Trends in the Epidemiology of Pediatric Severe Sepsis*
Between 1995 and 2005, the prevalence of severe sepsis in U.S. children steadily rose, due to a significant increase in the prevalence with Staphylococcus aureus in newborns, and in-hospital fatality associated with Streptococcus pneumoniae decreased. Expand
The epidemiology of severe sepsis in children in the United States.
Severe sepsis is a significant health problem in children and is associated with the use of extensive healthcare resources, and the mean length of stay and cost were 31 days and $40,600, respectively. Expand
Pediatric Severe Sepsis in U.S. Children’s Hospitals*
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Prevalence of pediatric severe sepsis increased in the studied U.S. children’s hospitals over the past 9 years, whereas resource utilization and mortality decreased, and the length of stay and costs decreased in both cohorts. Expand
Bacterial and Fungal Etiology of Sepsis in Children in the United States: Reconsidering Empiric Therapy*
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