Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage

@inproceedings{Echigo2011TrehaloseTS,
  title={Trehalose treatment suppresses inflammation, oxidative stress, and vasospasm induced by experimental subarachnoid hemorrhage},
  author={Ryosuke Echigo and Nobuyuki Shimohata and Kensuke Karatsu and Fumiko Yano and Yuko Kayasuga-Kariya and Ayano Fujisawa and Takayo Ohto and Yoshihiro Kita and Motonao Nakamura and Shigeki Suzuki and Manabu Mochizuki and Takao Shimizu and Ung-il Chung and Nobuo Sasaki},
  booktitle={Journal of Translational Medicine},
  year={2011}
}
Subarachnoid hemorrhage (SAH) frequently results in several complications, including cerebral vasospasm, associated with high mortality. Although cerebral vasospasm is a major cause of brain damages after SAH, other factors such as inflammatory responses and oxidative stress also contribute to high mortality after SAH. Trehalose is a non-reducing disaccharide in which two glucose units are linked by α,α-1,1-glycosidic bond, and has been shown to induce tolerance to a variety of stressors in… CONTINUE READING
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