Trehalose loading into red blood cells is accompanied with hemoglobin oxidation and membrane lipid peroxidation.

Abstract

One of the recent approaches to enhance desiccation tolerance in red blood cells (RBCs) is by loading trehalose. This process has been shown to increase the recovery of lyophilized RBCs; conversely, it results in cellular damage including hemoglobin oxidation and loss of membrane integrity. The purpose of this study was to further investigate the extent of… (More)
DOI: 10.1016/j.cryobiol.2008.12.003

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