Trehalose is an important mediator of Cap1p oxidative stress response in Candida albicans.

@article{Cao2008TrehaloseIA,
  title={Trehalose is an important mediator of Cap1p oxidative stress response in Candida albicans.},
  author={Ying-ying Cao and Yan Wang and Baodi Dai and Bin Wang and Hai Zhang and Zhenyu Zhu and Yonggang Xu and YongBing Cao and Yuanying Jiang and Guoqing Zhang},
  journal={Biological & pharmaceutical bulletin},
  year={2008},
  volume={31 3},
  pages={
          421-5
        }
}

• Ying-ying Cao, Yan Wang, +7 authors Guoqing Zhang
• Published 2008 in Biological & pharmaceutical bulletin

Trehalose, a nonreducing disaccharide which accumulates dramatically during stationary phase or under oxidative stress, is well known as a stress protectant in several organisms. Here we investigated the putative correlation of trehalose with Cap1p, which is a basic region-leucine zipper (bZip) transcription factor participating in oxidative stress tolerance in Candida albicans. HPLC-MS analysis showed that trehalose did not accumulate in the cap1/cap1 mutant during stationary phase. When the… CONTINUE READING

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