Trehalose induced modifications in the solvation pattern of N-methylacetamide.

@article{Paul2014TrehaloseIM,
  title={Trehalose induced modifications in the solvation pattern of N-methylacetamide.},
  author={S. Paul},
  journal={The journal of physical chemistry. B},
  year={2014},
  volume={118 4},
  pages={
          1052-63
        }
}
  • S. Paul, S. Paul
  • Published 2014
  • Chemistry, Medicine
  • The journal of physical chemistry. B
  • We have carried out molecular dynamics simulation to investigate the role of trehalose molecules on the change in the structural and dynamical properties of aqueous N-methylacetamide (NMA) solution. In this study, we considered six different trehalose concentrations ranging from 0 to 66%. Results are discussed in the framework of hydrophobic interactions between different methyl groups of NMA, structure of the solutions, and hydrogen bonding interactions between different solution species. We… CONTINUE READING
    Revisiting the conundrum of trehalose stabilization.
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