Trehalose Renders the Dauer Larva of Caenorhabditis elegans Resistant to Extreme Desiccation

@article{Erkut2011TrehaloseRT,
  title={Trehalose Renders the Dauer Larva of Caenorhabditis elegans Resistant to Extreme Desiccation},
  author={Cihan Erkut and S. Penkov and Hassan Khesbak and Daniela Vorkel and J. Verbavatz and K. Fahmy and T. Kurzchalia},
  journal={Current Biology},
  year={2011},
  volume={21},
  pages={1331-1336}
}
Water is essential for life on Earth. In its absence, however, some organisms can interrupt their life cycle and temporarily enter an ametabolic state, known as anhydrobiosis [1]. It is assumed that sugars (in particular trehalose) are instrumental for survival under anhydrobiotic conditions [2]. However, the role of trehalose remained obscure because the corresponding evidence was purely correlative and based mostly on in vitro studies without any genetic manipulations of trehalose metabolism… Expand
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The role of vitrification in anhydrobiosis.
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