Treg-enriched CD4+ T cells attenuate collagen synthesis in keloid fibroblasts.

Abstract

Keloid is an inflammatory and fibrotic disease with an unknown pathogenesis. Regulatory T cells (Tregs) of CD4+ lineage can suppress other effector CD4+ T cells and modulate the immune response. A relative decrease in the number of Tregs may be involved in the pathogenesis of inflammatory and fibrotic diseases. We therefore investigated the number of Tregs… (More)
DOI: 10.1111/exd.12368

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@article{Murao2014TregenrichedCT, title={Treg-enriched CD4+ T cells attenuate collagen synthesis in keloid fibroblasts.}, author={Naoki Murao and Ken-ichiro Seino and Toshihiko Hayashi and Masaki Ikeda and Emi Funayama and Hiroshi Furukawa and Yuhei Yamamoto and Akihiko Oyama}, journal={Experimental dermatology}, year={2014}, volume={23 4}, pages={266-71} }