Treatments (12 and 48 h) with systemic and brain-selective hypothermia techniques after permanent focal cerebral ischemia in rat.

@article{Clark2009TreatmentsA,
  title={Treatments (12 and 48 h) with systemic and brain-selective hypothermia techniques after permanent focal cerebral ischemia in rat.},
  author={Darren L Clark and Mark Penner and Shannon Wowk and Ian M Orellana-Jordan and Frederick Colbourne},
  journal={Experimental neurology},
  year={2009},
  volume={220 2},
  pages={391-9}
}
Mild hypothermia lessens brain injury when initiated after the onset of global or focal ischemia. The present study sought to determine whether cooling to approximately 33 degrees C provides enduring benefit when initiated 1 h after permanent middle cerebral artery occlusion (pMCAO, via electrocautery) in adult rats and whether protection depends upon… CONTINUE READING