Treatment with the interleukin-I receptor antagonist and soluble tumor necrosis factor receptor Fc fusion protein does not prevent endotoxin-induced preterm parturition in mice.

@article{Fidel1997TreatmentWT,
  title={Treatment with the interleukin-I receptor antagonist and soluble tumor necrosis factor receptor Fc fusion protein does not prevent endotoxin-induced preterm parturition in mice.},
  author={Paul L. Fidel and Roberto Romero and Jason Cutright and Nelson Wolf and Ricardo Pay{\'a}n Gom{\'e}z and Heriberto Araneda and Miguel de J. Ram{\'i}rez and Bo Hyun Yoon},
  journal={Journal of the Society for Gynecologic Investigation},
  year={1997},
  volume={4 1},
  pages={22-6}
}
OBJECTIVE To determine whether the administration of anticytokine agents, the interleukin-1 receptor antagonist (IL-1ra) and a soluble tumor necrosis factor receptor Fc fusion protein (sTNFR-Fc), prevents endotoxin-induced preterm delivery in mice. METHODS C3H/HeN pregnant mice at 15 days of gestation (70% gestation) were randomized to receive phosphate… CONTINUE READING