Treatment with anti-TNF monoclonal antibody (c5N) reduces the extent of induced endometriosis in the baboon.

@article{Falconer2006TreatmentWA,
  title={Treatment with anti-TNF monoclonal antibody (c5N) reduces the extent of induced endometriosis in the baboon.},
  author={Henrik Falconer and Jason M. Mwenda and Daniel C. Chai and Carrie Lynne Wagner and Xiang Yang Song and Attila Mih{\'a}lyi and Peter Simsa and Cleophas K. Kyama and Freddy J. Cornillie and A Enrique Bergqvist and Gabriel Fried and Thomas D'hooghe},
  journal={Human reproduction},
  year={2006},
  volume={21 7},
  pages={
          1856-62
        }
}
BACKGROUND Inflammatory cytokines, including interleukin (IL)-1, IL-6, IL-8 and tumour necrosis factor-alpha (TNF-alpha), are important in the pathogenesis of endometriosis. We assessed the efficacy of anti-TNF monoclonal antibody (mAb, c5N), known to prevent induced endometriosis in baboons, in reducing established endometriosis in baboons. METHODS This prospective, randomized, blinded, controlled study was conducted in baboons at the Institute of Primate Research (IPR), Nairobi, Kenya… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 33 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 29 REFERENCES

Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy

  • TA Gardiner, DS Gibson, TE de Gooyer, VF de la Cruz, DM McDonald, AW Stitt
  • Am J Pathol
  • 2005
2 Excerpts

Similar Papers

Loading similar papers…