Treatment with an Anabolic-Androgenic Steroid Affects Anxiety-Related Behavior and Alters the Sensitivity of Cortical GABAA Receptors in the Rat

@article{Bitrn1993TreatmentWA,
  title={Treatment with an Anabolic-Androgenic Steroid Affects Anxiety-Related Behavior and Alters the Sensitivity of Cortical GABAA Receptors in the Rat},
  author={D. Bitr{\'a}n and C. Kellogg and R. J. Hilvers},
  journal={Hormones and Behavior},
  year={1993},
  volume={27},
  pages={568-583}
}
  • D. Bitrán, C. Kellogg, R. J. Hilvers
  • Published 1993
  • Chemistry, Medicine
  • Hormones and Behavior
  • The putative psychotropic effect of the anabolic-androgenic steroid, testosterone propionate (TP), was determined in intact adult male rats after 1 or 2 weeks of continued exposure via subcutaneously implanted capsules. Behavior was assessed in a novel open-field arena and in the elevated plus-maze. In addition, gamma-aminobutyric acid (GABA)-stimulated 36chloride (Cl-) influx was determined in cerebral cortical synaptoneurosomes as a function of TP exposure. The weight of the prostate gland… CONTINUE READING
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