Treatment with alendronate prevents fractures in women at highest risk: results from the Fracture Intervention Trial.

@article{Ensrud1997TreatmentWA,
  title={Treatment with alendronate prevents fractures in women at highest risk: results from the Fracture Intervention Trial.},
  author={Kristine E Ensrud and Dennis M. Black and Lisa Palermo and Doug Bauer and Elizabeth Barrett-Connor and Sara A. Quandt and Desmond E. Thompson and David Karpf},
  journal={Archives of internal medicine},
  year={1997},
  volume={157 22},
  pages={2617-24}
}
BACKGROUND The efficacy of antiresorptive therapy in preventing fractures in women at highest fracture risk, such as very elderly women or those with severe osteoporosis, is uncertain. PARTICIPANTS AND METHODS Using data from a double-blind, randomized, placebo-controlled clinical trial that enrolled 2027 postmenopausal women aged 55 to 81 years with low femoral neck bone mineral density (BMD) and existing vertebral fractures, we examined the consistency of the effect of treatment with… CONTINUE READING
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