Treatment with Mesna and n-3 polyunsaturated fatty acids ameliorates experimental ulcerative colitis in rats.

Abstract

Oxidative damage is a central feature of ulcerative colitis. Here, we tested whether the antioxidant Mesna, when administered alone or in combination with n-3 polyunsaturated fatty acids (n-3 PUFAs), affects the outcome of dextran sodium sulphate (DSS)-induced ulcerative colitis in rats. After the induction of colitis, DSS-treated rats were further treated… (More)
DOI: 10.1111/iep.12163

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@article{Triantafyllidis2015TreatmentWM, title={Treatment with Mesna and n-3 polyunsaturated fatty acids ameliorates experimental ulcerative colitis in rats.}, author={Ioannis Triantafyllidis and Theofilos Poutahidis and Ioannis A Taitzoglou and Isaak I Kesisoglou and Charalampos Lazaridis and Dimitrios Botsios}, journal={International journal of experimental pathology}, year={2015}, volume={96 6}, pages={433-43} }