Treatment with Cefotaxime Affects Expression of Conjugation Associated Proteins and Conjugation Transfer Frequency of an IncI1 Plasmid in Escherichia coli

@inproceedings{Mller2017TreatmentWC,
  title={Treatment with Cefotaxime Affects Expression of Conjugation Associated Proteins and Conjugation Transfer Frequency of an IncI1 Plasmid in Escherichia coli},
  author={Thea S. B. M\oller and Gang Liu and Anders Boysen and Line E. Thomsen and Freja Lea L{\"u}thje and Sisse Mortensen and Jakob M\oller-Jensen and John Elmerdahl Olsen},
  booktitle={Front. Microbiol.},
  year={2017}
}
Horizontal gene transfer (HGT) is the major mechanism responsible for spread of antibiotic resistance. Antibiotic treatment has been suggested to promote HGT, either by directly affecting the conjugation process itself or by selecting for conjugations subsequent to DNA transfer. However, recent research suggests that the effect of antibiotic treatment on plasmid conjugation frequencies, and hence the spread of resistance plasmids, may have been overestimated. We addressed the question by… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 41 references

A new mathematical model for relative quantification in real-time RT-PCR.

Nucleic acids research • 2001
View 6 Excerpts
Highly Influenced

Microbiological effects of sublethal levels of antibiotics

Nature Reviews Microbiology • 2014
View 1 Excerpt
Highly Influenced

Impact of antibiotic treatments on the expression of the R plasmid tra genes and on the host innate immune activity during pRAS 1 bearing Aeromonas hydrophila infection in zebrafish ( Danio rerio )

L. Cantas, P. J. Midtlyng, H. Sorum
BMCMicrobiol • 2012
View 4 Excerpts
Highly Influenced

Horizontal Gene Exchange in Environmental Microbiota

Front. Microbio. • 2011
View 1 Excerpt
Highly Influenced

The complete genome sequence of Escherichia coli K-12.

Science • 1997
View 1 Excerpt
Highly Influenced

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