Treatment responsive GABA(B)-receptor limbic encephalitis presenting as new-onset super-refractory status epilepticus (NORSE) in a deployed U.S. soldier.

@article{Hainsworth2014TreatmentRG,
  title={Treatment responsive GABA(B)-receptor limbic encephalitis presenting as new-onset super-refractory status epilepticus (NORSE) in a deployed U.S. soldier.},
  author={Jeffrey Brian Hainsworth and Akira A Shishido and Brett James Theeler and Craig Grason Carroll and Rebecca Ellen Fasano},
  journal={Epileptic disorders : international epilepsy journal with videotape},
  year={2014},
  volume={16 4},
  pages={486-93}
}
A 23-year-old, previously healthy, deployed U.S. soldier presented with bilateral temporal lobe seizures recalcitrant to multiple antiepileptic drugs and anti-seizure anaesthetic agents. He received methylprednisolone, intravenous immunoglobulins, plasma exchange, and rituximab for presumed autoimmune encephalitis before achieving seizure freedom. Six weeks after presentation, the aetiology of his refractory seizures was found to be due to autoantibodies targeting the anti-GABA(B)-receptor… CONTINUE READING