Treatment responses in five patients with Ribbing disease including two with 466C>T missense mutations in TGFβ1.


OBJECTIVE To assess 5-year treatment responses and TGFB1 gene abnormalities in five patients with ribbing disease. METHODS PCR analysis and bidirectional sequencing of TGFβ1 exons 1 through 7 were performed in all five patients. RESULTS The five patients, four women and one man with a mean age of 34 years at symptom onset, shared the following features… (More)
DOI: 10.1016/j.jbspin.2013.01.007


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics