Treatment response to ritonavir-boosted tipranavir versus ritonavir-boosted lopinavir in HIV-1 patients with higher lopinavir mutation scores.

@article{Walmsley2007TreatmentRT,
  title={Treatment response to ritonavir-boosted tipranavir versus ritonavir-boosted lopinavir in HIV-1 patients with higher lopinavir mutation scores.},
  author={Sharon Lynn Walmsley and Laurent Cotte and Stefano Rusconi and Douglas J. Ward and Charles B. Hicks and Ulrich Meier and Hern{\'a}n Valdez and Charles A. Boucher},
  journal={AIDS},
  year={2007},
  volume={21 16},
  pages={2245-8}
}
Week 48 HIV-RNA treatment response to the protease inhibitor tipranavir co-administered with ritonavir was compared with that of lopinavir co-administered with ritonavir in patients whose baseline isolates had varying lopinavir genotypic mutation scores. With increasing lopinavir mutation scores, the proportion of patients achieving a week 48 treatment response was increased in the tipranavir/ritonavir compared with the lopinavir/ritonavir arm. Tipranavir/ritonavir therapy improves treatment… CONTINUE READING