Treatment-resistant depression in late life.

  title={Treatment-resistant depression in late life.},
  author={Benoit H. Mulsant and Bruce G. Pollock},
  journal={Journal of geriatric psychiatry and neurology},
  volume={11 4},
Depression is the most prevalent functional psychiatric disorder in late life. It is associated with a high risk of mortality from comorbid medical illness and from suicide. Successful antidepressant treatment is one of the most effective ways to reduce disability, prevent morbidity, and improve quality of life in an older depressed patient. Treatment-resistant depression is a common clinical problem, reported to affect up to one-third of older depressed patients. However, published data on… CONTINUE READING

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