Treatment outcomes of surgery, antifungal therapy and immunotherapy in ocular and vascular human pythiosis: a retrospective study of 18 patients.

@article{Permpalung2015TreatmentOO,
  title={Treatment outcomes of surgery, antifungal therapy and immunotherapy in ocular and vascular human pythiosis: a retrospective study of 18 patients.},
  author={Nitipong Permpalung and Navaporn Worasilchai and Rongpong Plongla and Sikarin Upala and Anawin Sanguankeo and Leilani Paitoonpong and Leonel A Mendoza and Ariya Chindamporn},
  journal={The Journal of antimicrobial chemotherapy},
  year={2015},
  volume={70 6},
  pages={1885-92}
}
OBJECTIVES Human pythiosis is a life-threatening disease for which no standard treatment protocols with proven efficacy exist. We present the results of our institutional pythiosis treatment protocol, composed of surgery, antifungal agents, iron chelator (only vascular cases) and immunotherapy. METHODS We retrospectively analysed patients with proven vascular and ocular pythiosis in King Chulalongkorn Memorial Hospital from April 2003 to May 2013. Fisher's exact test and Wilcoxon's rank-sum… CONTINUE READING

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