Treatment options and considerations for hypertensive patients to prevent dementia

@article{Hernandorena2017TreatmentOA,
  title={Treatment options and considerations for hypertensive patients to prevent dementia},
  author={Intza Hernandorena and Emmanuelle Duron and Jean-S{\'e}bastien Vidal and Olivier Hanon},
  journal={Expert Opinion on Pharmacotherapy},
  year={2017},
  volume={18},
  pages={1000 - 989}
}
ABSTRACT Introduction: Dementia is a worldwide health concern, which leads to loss of autonomy. To date no curative treatment is available so focus on modifiable risk factors is of particular interest. Hypertension, particularly midlife high blood pressure, has been associated with an increased risk for cognitive decline and dementia including vascular dementia (VAD) and Alzheimer disease (AD). In this context, antihypertensive treatments might have a preventive effect. The objective of this… 
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[Arterial hypertension, cognitive disorders and dementia: a view of a cardiologist].
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The importance of the interdisciplinary approach to treatment of cognitive impairment by cardiologists and/or therapists, together with neurologists, as well as complex treatment regimens, including correction of risk factors and neuroprotective therapy, is highlighted.
Antihypertensive Medication Classes and the Risk of Dementia: A Systematic Review and Network Meta-analysis.
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The burden of dementia risk in aging PLHIV is higher than that in the general population, particularly in the most vulnerable clusters, so a comprehensive and preventative neurogeriatric healthcare response linked with HIV communities and dementia associations should be urgently put in place.
Prevalence of risk factors for dementia in middle- and older- aged people registered in Primary Health Care
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Evaluating the prevalence of main risk factors for dementia in individuals registered in Primary Health Care in Brazil and their relationship with sex and age group can guide interventions, especially in developing countries.
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By counteracting early on the cardiovascular risk factor load and the pathological processes leading to increased aminoterminal natriuretic peptide (NT-proNP) level, the risk of dementia could be significantly reduced, and an increased NP level should be considered as a direct marker of neuronal damage.
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Dementia prevalence was high and diagnosed dementia was associated with lower levels of vitamin D, suggesting vitamin D is a modifiable factor, opening up essential perspectives for public health policies.
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Felodipine has a sufficient evidence base of clinical trials demonstrating not only good antihypertensive and antianginal potential of the drug, but also the nephroprotection and cerebroprotection properties.
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A progressive increase in the plasma level of TC and LDLc from mild to severe hypertensive patients is revealed which could be a pointer to the fact that abnormalities in lipid metabolism might plays a significant role in the development and severity of hypertension.
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