Treatment of warfarin-related intracranial hemorrhage: a comparison of prothrombin complex concentrate and recombinant activated factor VII.

@article{Pinner2010TreatmentOW,
  title={Treatment of warfarin-related intracranial hemorrhage: a comparison of prothrombin complex concentrate and recombinant activated factor VII.},
  author={Nathan A Pinner and April C Hurdle and Carrie S Oliphant and Anne B. Reaves and Bob L Lobo and Allen Sills},
  journal={World neurosurgery},
  year={2010},
  volume={74 6},
  pages={631-5}
}
OBJECTIVE Warfarin-related intracranial hemorrhage (ICH) is a devastating complication of warfarin therapy. Several studies have demonstrated successful correction of the international normalized ratio (INR) using prothrombin complex concentrate (PCC) or recombinant activated factor VII (rFVIIa). To our knowledge, no study has directly compared these agents for treatment of warfarin-related ICH. METHODS We retrospectively reviewed the charts of 15 patients who received rFVIIa and 9 who… CONTINUE READING
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