Treatment of vitiligo with broadband ultraviolet B and vitamins

@article{Don2006TreatmentOV,
  title={Treatment of vitiligo with broadband ultraviolet B and vitamins},
  author={Philip C. Don and Aurel O. Iuga and Anne Dacko and Kathleen Hardick},
  journal={International Journal of Dermatology},
  year={2006},
  volume={45}
}
Background  While oral psoralen plus ultraviolet A (PUVA) remains the most popular therapeutic modality for vitiligo, recent reports have shown that narrowband ultraviolet B (UVB) also induces significant repigmentation. In this study we evaluated the efficacy of broadband UVB on actively spreading, progressive vitiligo in patients who had been followed for many months (12 or more) in our practice, who continued to depigment despite treatment. 

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References

SHOWING 1-10 OF 15 REFERENCES

UV‐B radiation microphototherapy. An elective treatment for segmental vitiligo

TLDR
Previous studies have suggested the effectiveness of UV‐B radiation in generalized vitiligo therapy, but there was no evidence to support the same role for segmental Vitiligo (SV), so further studies are needed to confirm this role.

PUVA treatment of vitiligo: a retrospective study of Turkish patients

TLDR
This study attempts to evaluate the efficacy of the treatment in Turkish vitiligo patients with Psoralen plus ultraviolet A (PUVA) by evaluating the response of patients to the treatment.

Treatment of vitiligo with UV-B radiation vs topical psoralen plus UV-A.

TLDR
According to the results, the treatment of patients with vitiligo with 311-nm UV-B radiation is as efficient as with topical PUVA and has fewer adverse effects.

The efficacy of low‐dose oral corticosteroids in the treatment of vitiligo patients

TLDR
The clinical efficacy of low‐dose oral corticosteroids was assessed to minimize the side-effects in actively spreading vitiligo patients.

Vitiligo. An overview of therapeutic approaches.

Depigmentation therapy in vitiligo universalis with topical 4-methoxyphenol and the Q-switched ruby laser.

TLDR
Depigmentation therapy using a 4-MP cream and/or QSR laser therapy is an effective and safe method to remove disfiguring residual pigment in patients with vitiligo universalis and patients should be warned that repigmentation may occur, even after total depigmentation has been achieved.

Acceleration of Repigmentation in Vitiligo by Topical Minoxidil in Patients on Photochemotherapy

TLDR
Interviewing the psoriatics, retrospectively, from among these settlers to evaluate the effect of chloroquine on the course of their psoriasis, found a positive correlation between the two events.

Mechanisms of phototherapy of vitiligo.

TLDR
Because there are no melanocytes in fully developed vitiligo macules, the autoimmune mechanism would appear to involve progressive destruction of melanocytes by autoantibody-dependent cellular cytotoxicity or by cytotoxic T lymphocytes.

Improvement of vitiligo after oral treatment with vitamin B12 and folic acid and the importance of sun exposure.

TLDR
Folic acid and vitamin B12 supplementation combined with sun exposure can induce repigmentation better than either the vitamins or sun exposure alone.