Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells.

@article{Mahmood2001TreatmentOT,
  title={Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells.},
  author={A. Rupam Mahmood and Dunyue Lu and Lei Wang and Yi Li and Mei Lu and Michael Chopp},
  journal={Neurosurgery},
  year={2001},
  volume={49 5},
  pages={1196-203; discussion 1203-4}
}
OBJECTIVE To study the effect of bone marrow stromal cells administered intravenously to female rats subjected to traumatic brain injury. METHODS We injected marrow stromal cells harvested from male rat bone marrow (n = 24) into the tail vein of the female rat (n = 8) 24 hours after traumatic brain injury; the rats were killed at Day 7 or 14 after treatment. The neurological function of the rats was evaluated using the rotarod test and the neurological severity score. The distribution of the… CONTINUE READING
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