Treatment of toxic epidermal necrolysis with cyclosporin A.

  title={Treatment of toxic epidermal necrolysis with cyclosporin A.},
  author={Juan Ar{\'e}valo and J. A. Lorente and Carlos Gonz{\'a}lez-Herrada and J Jim{\'e}nez-Reyes},
  journal={The Journal of trauma},
  volume={48 3},
BACKGROUND Toxic epidermal necrolysis (TEN) is a severe skin disorder characterized by separation of the dermal-epidermal junction, as is observed in second-degree superficial burns. It has been proposed that immunosuppressive treatment may improve prognosis of patients with TEN. METHODS We report here a case series of patients with TEN treated with cyclosporin A (CSA) without other concomitant immunosuppressive agent. These patients (n = 11) were consecutively admitted to our Intensive Care… CONTINUE READING