Treatment of superficial bladder tumors with intravesical recombinant interferon alpha-2a.

@article{Ackermann1988TreatmentOS,
  title={Treatment of superficial bladder tumors with intravesical recombinant interferon alpha-2a.},
  author={Daniel Ackermann and Christina Biedermann and Gregory G Bailly and Urs E Studer},
  journal={Urologia internationalis},
  year={1988},
  volume={43 2},
  pages={85-8}
}
In a prospective study, the toxicity and efficacy of an instillation therapy with recombinant interferon alpha-2a (rIFN-alpha-2a) were evaluated in 12 patients with superficial bladder tumors. Treatment consisted of 8 weekly instillations of 54 X 10(6) IU rIFN-alpha-2a in 50 ml saline. Two weeks after completion of the instillation therapy, the tumor status was assessed with cystoscopy, biopsy and bladder wash-out cytology. Two partial responses, 1 no change and 2 progressive disease were seen… CONTINUE READING