Treatment of stroke with liposomal neuroprotective agents under cerebral ischemia conditions.

@article{Fukuta2015TreatmentOS,
  title={Treatment of stroke with liposomal neuroprotective agents under cerebral ischemia conditions.},
  author={Tatsuya Fukuta and Takayuki Ishii and Tomohiro Asai and Akihiko Sato and Takashi Kikuchi and Kosuke Shimizu and Tetsuo Minamino and Naoto Oku},
  journal={European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V},
  year={2015},
  volume={97 Pt A},
  pages={1-7}
}
Since the proportion of patients given thrombolytic therapy with tissue plasminogen activator (t-PA) is very limited because of the narrow therapeutic window, the development of new therapies for ischemic stroke has been desired. We previously reported that liposomes injected intravenously accumulate in the ischemic region of the brain via disruption of the… CONTINUE READING