Treatment of stage D prostatic carcinoma with megestrol acetate

@article{Block1981TreatmentOS,
  title={Treatment of stage D prostatic carcinoma with megestrol acetate},
  author={M. Block and Philip D. Bonomi and K M Anderson and Janet M. Wolter and J. L. Showel and Dennis Pessis and Robert E. Slayton},
  journal={Journal of Surgical Oncology},
  year={1981},
  volume={17}
}
Nine previously untreated patients with stage D prostatic carcinoma received megestrol acetate 40 mg orally three times daily. Responses included five partial regressions, two stabilizations, and two progressions. Duration of response ranged from 3 + to 33 + months, with a mean of 11.7 months and a median of 12 months. Three of five patients who had failed prior hormonal therapy remained objectively stable while receiving megestrol acetate. No gastrointestinal toxicity, gynecomastia, fluid… 
11 Citations
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