Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor.

@article{Setoguchi2004TreatmentOS,
  title={Treatment of spinal cord injury by transplantation of fetal neural precursor cells engineered to express BMP inhibitor.},
  author={Takao Setoguchi and Kinichi Nakashima and Takumi Takizawa and M. D. K. Yanagisawa and Wataru Ochiai and Masaru Okabe and Kazunori Yone and Setsuro Komiya and Tetsuya Taga},
  journal={Experimental neurology},
  year={2004},
  volume={189 1},
  pages={33-44}
}
Spontaneous recovery after spinal cord injury is limited. Transplantation of neural precursor cells (NPCs) into lesioned adult rat spinal cord results in only partial functional recovery, and most transplanted cells tend to differentiate predominantly into astrocytes. In order to improve functional recovery after transplantation, it is important that transplanted neural precursor cells appropriately differentiate into cell lineages required for spinal cord regeneration. In order to modulate the… CONTINUE READING
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