Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.

@article{Ewend2007TreatmentOS,
  title={Treatment of single brain metastasis with resection, intracavity carmustine polymer wafers, and radiation therapy is safe and provides excellent local control.},
  author={Matthew G. Ewend and Steven Brem and Mark R. Gilbert and Robert Goodkin and Paul L. Penar and Mahesh Varia and Sharon Cush and Lisa A. Carey},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2007},
  volume={13 12},
  pages={3637-41}
}
PURPOSE To define the safety and efficacy of carmustine polymer wafers when added to a regimen of surgery and external beam radiotherapy for treatment of a single brain metastasis. EXPERIMENTAL DESIGN Adult patients underwent craniotomy for a single brain metastasis, and carmustine polymer wafers were placed in the tumor resection cavity. Patients then received whole-brain radiotherapy and were followed for patterns of recurrence in the central nervous system, toxicity, and survival… CONTINUE READING