Treatment of severe mania with intravenous magnesium sulphate as a supplementary therapy

@article{Heiden1999TreatmentOS,
  title={Treatment of severe mania with intravenous magnesium sulphate as a supplementary therapy},
  author={Angela Heiden and Richard D. Frey and Otto Presslich and T. Blasbichler and Siegfried Kasper},
  journal={Psychiatry Research},
  year={1999},
  volume={89},
  pages={239-246}
}
Ten patients with severe, therapy-resistant manic agitation received magnesium sulphate infusions with a continuous magnesium (Mg) flow of approximately 200 mg/h (4353+/-836 mg/day; daily monitored Mg plasma level: 2.44+/-0.34 mmol/l) for periods ranging from 7 to 23 days. Concomitant psychotropic treatment consisted of lithium (n = 10), haloperidol (n = 5) and clonazepam (n = 10). During i.v. Mg treatment the mean values of the maximum dosages of neuroleptics (in chlorpromazine equivalents… CONTINUE READING

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