Treatment of restless legs syndrome: An evidence‐based review and implications for clinical practice

@article{Trenkwalder2008TreatmentOR,
  title={Treatment of restless legs syndrome: An evidence‐based review and implications for clinical practice},
  author={Claudia Trenkwalder and W. Hening and Pasquale Montagna and Wolfgang Hermann Oertel and Richard P. Allen and Arthur S. Walters and Jo{\~a}o Costa and Karin Stiasny‐Kolster and Cristina Sampaio},
  journal={Movement Disorders},
  year={2008},
  volume={23}
}
Only in the last three decades, the restless legs syndrome (RLS) has been examined in randomized controlled trials. The Movement Disorder Society (MDS) commissioned a task force to perform an evidence‐based review of the medical literature on treatment modalities used to manage patients with RLS. The task force performed a search of the published literature using electronic databases. The therapeutic efficacy of each drug was classified as being either efficacious, likely efficacious… 

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Iron sulfate does not appear to be an effective empiric treatment for restless legs syndrome and should not be considered as a treatment for insomnia.

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TLDR
The results suggested that gabapentin is an effective drug for the management of RLS in hemodialysis patients, and was significantly superior to levodopa for sleep quality, sleep latency, and sleep disturbance.

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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