Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation

@article{Thomas2000TreatmentOR,
  title={Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation},
  author={X. Thomas and Herv{\'e} Dombret and Catherine Cordonnier and Arnaud Pigneux and Claude Gardin and Agn{\`e}s Guerci and Anne Vekhoff and A. M. Sadoun and Aspasia Stamatoullas and Nathalie Fegueux and F r{\'e}d{\'e}ric Maloisel and J Y Cahn and Oum{\'e}daly Reman and Nicole Gratecos and Christian Berthou and Françoise Huguet and Pavel P Kotou{\vc}ek and Philippe Travade and Agn{\'e}s Buzyn and Thierry D E Revel and J P Vilque and P Y Naccache and Christine Chomienne and Laurent Degos and Pierre Fenaux},
  journal={Leukemia},
  year={2000},
  volume={14},
  pages={1006-1013}
}
The purpose of this study was to assess the safety and efficacy of stem cell transplantation (SCT) mainly autologous SCT as consolidation therapy in APL patients who relapsed and achieved a second complete remission (CR2). Fifty adult patients with a first relapsed APL, of whom 39 had been previously treated with ATRA, entered a multicenter trial of oral ATRA until complete remission (CR) achievement followed by timed sequential chemotherapy (EMA combining etoposide 200 mg/m2/day for 3 days… CONTINUE READING

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References

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Showing 1-10 of 45 references

A randomized comparison of all - trans retinoic acid ( ATRA ) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia

  • C Cordonnier, F Dreyfus, +10 authors JP Vernant
  • Blood
  • 1999

Recent advances in the biology and treatment of acute promyelocytic leukemia

  • JL Slack
  • Proc Am Soc Clin Oncol
  • 1998

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