Treatment of refractory melasma with combination of topical 5% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients

@article{Shaikh2014TreatmentOR,
  title={Treatment of refractory melasma with combination of topical 5\% magnesium ascorbyl phosphate and fluorescent pulsed light in Asian patients},
  author={Zafar Iqbal Shaikh and Ashar A Mashood},
  journal={International Journal of Dermatology},
  year={2014},
  volume={53}
}
BACKGROUND Melasma is an acquired disorder of hypermelanosis of great psychosocial concern. [...] Key MethodMATERIALS AND METHODS Patients of skin types III-V with refractory melasma were treated for 12 weeks with topical application of 5% MAP and three sessions of FPL (570-950 nm) at 3, 6, and 9 weeks (fluence 12-14 J/cm(2) , pulse width 15 ms, and spot size 3 cm(2) ). They were followed up for another 12 weeks to assess the persistence of treatment benefit.Expand
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Melasma: A critical analysis of clinical trials investigating treatment modalities published in the past 10 years
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Melasma is an acquired disorder of facial pigmentation which is a treatment challenge and needs to be treated with a variety of medications.
Background and different treatment modalities for melasma: Conventional and nanotechnology-based approaches
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The current review presents the approaches adopted to treat melasma and reviews the active molecules counteracting the melanogenesis process and the diverse nanotechnology-based delivery systems, which showed successful topical delivery of hypopigmenting agents for the treatment of melasma.
Topical Tranexamic Acid Versus Topical Ascorbic Acid in the Treatment of Melasma: Randomized Clinical Trial
  • A. A.
  • Clinical Dermatology Open Access Journal
  • 2019
Background: Melasma is an acquired hypermelanosis characterized by symmetrical, irregular light-to-dark-brown macules & patches on sun-exposed area, especially on the face. Tranexamic acid is a…
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TLDR
Vitamin E, niacinamide, polypodium leucotomos, pycnogenol, grape seed extract, amino fruit acids, phytic acid, zinc, silymarin, Korean red ginseng powder, plant extracts, and parsley all have well‐demonstrated evidence of antioxidant properties, and these substances have been studied in the context of skin hyperpigmentation.
A Meta-analysis-Based Assessment of Intense Pulsed Light for Treatment of Melasma
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A meta-analysis showed that IPL-based combination therapy for melasma can effectively reduce the MASI score and result in higher satisfaction among patients, indicating an effective method for treatment of the condition.
The efficacy of energy‐based devices combination therapy for melasma
TLDR
Evaluation of efficacy of energy‐based devices combination therapy for melasma finds application of topical lightening agents in combination with laser therapy leads to higher efficacy with less adverse effects (post‐inflammatory hyperpigmentation) and rebound of melasma.
Salicylic acid peeling combined with vitamin C mesotherapy versus salicylic acid peeling alone in the treatment of mixed type melasma: A comparative study
TLDR
SA peel combined with vitamin C mesotherapy is a safe and effective alternative for the treatment of melasma with no significant side effects and minimal downtime.
Study of autologous platelet‐rich‐plasma versus its combination with intense pulsed light in treatment of melasma
TLDR
The improvement ofmelasma with regression of melasma scores after PRP treatment is an important finding and this study provides the first comparison between PRP versus its combination with IPL in melasma treatment.
Invited Discussion on: A Meta-analysis-Based Assessment of Intense Pulsed Light for Treatment of Melasma
Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of
Effect of Topical Application of the Cream Containing Magnesium 2% on Treatment of Diaper Dermatitis and Diaper Rash in Children A Clinical Trial Study.
TLDR
Based on the finding of this study, Mg is effective on treatment of diaper dermatitis and could be used for treating diaper dermatopathy and other types of dermatitis.
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