Treatment of pre‐menopausal advanced breast cancer with goserelin—a long‐acting luteinizing hormone releasing hormone agonist

@article{Brambilla1992TreatmentOP,
  title={Treatment of pre‐menopausal advanced breast cancer with goserelin—a long‐acting luteinizing hormone releasing hormone agonist},
  author={Cristina Brambilla and A. Escobedo and R Artioli and Mar{\'i}a Jos{\'e} Lechuga and Manuela Motta},
  journal={Anti-Cancer Drugs},
  year={1992},
  volume={3},
  pages={3–8}
}
Twenty-two pre-menopausal evaluable patients with advanced breast cancer (median age 39 years; ER positive 19, unknown three; prior adjuvant chemotherapy 16) were treated with the LHRH agonist goserelin depot (Zoladex*). Serum levels of 17 β-estradiol and progesterone were suppressed by goserelin within 3–4 weeks of therapy, while serum leuteinizing hormone and follicle stimulating hormone titers remained in the low level of the normal range. Complete or partial response was documented in seven… 
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  • A. Manni
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