Treatment of postherpetic neuralgia: a review of therapeutic options.

  title={Treatment of postherpetic neuralgia: a review of therapeutic options.},
  author={Charles E. Argoff and Nathaniel P. Katz and Miroslav Backonja},
  journal={Journal of pain and symptom management},
  volume={28 4},
Postherpetic neuralgia (PHN) is a disabling consequence of the reactivation of the varicella zoster infection. The observation that patients with PHN experience various types of pain suggests that multiple pathophysiologic mechanisms are involved, which may include the peripheral and central nervous systems. A reasonable initial strategy would involve selecting from among multiple agents that have complementary mechanisms of action and that have been proven effective in controlled clinical… CONTINUE READING