Treatment of polycythemia vera with hydroxyurea and pipobroman: final results of a randomized trial initiated in 1980.

@article{Kiladjian2011TreatmentOP,
  title={Treatment of polycythemia vera with hydroxyurea and pipobroman: final results of a randomized trial initiated in 1980.},
  author={Jean-Jacques Kiladjian and Sylvie Chevret and Christine C Dosquet and Christine Chomienne and J. D. Rain},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2011},
  volume={29 29},
  pages={3907-13}
}
PURPOSE The overall impact of hydroxyurea (HU) or pipobroman treatments on the long-term outcome of patients with polycythemia vera (PV) has not been assessed in randomized studies. We report final analyses from the French Polycythemia Study Group (FPSG) study, which randomly assigned HU versus pipobroman as first-line therapy in 285 patients younger than age 65 years. PATIENTS AND METHODS The full methodology has been described previously. FPSG results were updated with a median follow-up of… CONTINUE READING
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