Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: A review of 5 clinical studies

@article{Suter2006TreatmentOP,
  title={Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: A review of 5 clinical studies},
  author={Andy Suter and Silvia Bommer and Jordan Rechner},
  journal={Advances in Therapy},
  year={2006},
  volume={23},
  pages={179-190}
}
Extracts from the seed of the horse chestnut (Aesculus hippocastanum L.) have traditionally been used to treat patients with chronic venous insufficiency and to alleviate its associated symptoms, including lower leg swelling. The efficacy of preparations that contain horse chestnut seed extract (HCSE) is believed to be due largely to an inhibitory effect on the catalytic breakdown of capillary wall proteoglycans. Aesculaforce® is a fresh plant HCSE that is available as an oral tincture, as… 

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