Treatment of patients with metastasizing colo-rectal carcinoma with mouse monoclonal antibodies (Moab 17-1A): a progress report.

@article{Frdin1986TreatmentOP,
  title={Treatment of patients with metastasizing colo-rectal carcinoma with mouse monoclonal antibodies (Moab 17-1A): a progress report.},
  author={J E Fr{\"o}din and Peter Biberfeld and Birger Christensson and P Philstedt and Staffan Sundelius and Mikael Sylv{\'e}n and Britta E. Wahren and Hilary Koprowski and H{\aa}kan Mellstedt},
  journal={Hybridoma},
  year={1986},
  volume={5 Suppl 1},
  pages={S151-61}
}
Eight patients with metastasizing colo-rectal carcinoma have been treated with Moab 17-1A. Before infusion the antibodies were incubated in vitro with isolated autologous blood mononuclear cells (AMC) enriched for monocytes/macrophages. Treatment was given in repeated courses (2-4 times) up to a maximum amount of 1000 mg Moab 17-1A. Two patients had an… CONTINUE READING