Treatment of multiple sclerosis: role of natalizumab

  title={Treatment of multiple sclerosis: role of natalizumab},
  author={G. Comi},
  journal={Neurological Sciences},
  • G. Comi
  • Published 2009
  • Medicine
  • Neurological Sciences
  • The results on relapse rate and disease progression of available drugs for multiple sclerosis are shown, as well as their most relevant side effects. Results from pivotal and long-term follw-up studies support the efficacy and safety of intererons and glatiramer acetate. The treatment with mitoxantrone is limited by the occurrence of infertility, cardiotoxicy and leukaemia. Efficacy and tolerability of natalizumab are undisputable, compared to other drugs. Risks related to its treatment are PML… CONTINUE READING
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