Treatment of molluscum contagiosum with cantharidin: a practical approach.

  title={Treatment of molluscum contagiosum with cantharidin: a practical approach.},
  author={Erin F D Mathes and Ilona J Frieden},
  journal={Pediatric annals},
  volume={39 3},
          124-8, 130
Molluscum contagiosum is very common. In this article we discuss the use of cantharidin as a treatment option for molluscum contagiosum and give detailed information about distribution sources, how to apply it, and caveats regarding its use.Molluscum contagiosum is a common viral disease of childhood caused by a poxvirus, which presents with small, firm, dome-shaped, umbilicated papules. It is generally benign and self-limited, with spontaneous resolution within 6 months to several years… 

Beetle juice: a guide for the use of cantharidin in the treatment of molluscum contagiosum

Current literature regarding MC is summarized and particular focus is placed on the use of cantharidin for treating MC, including a review of the literature and detailed instructions for its use.

Cantharidin: A well-tolerated and effective therapy for Molluscum contagiosum in children

It is demonstrated that cantharidin could be considered a front line therapy for MC in children in children through the efficacy and tolerability of a non-painful treatment intervention with topical canthARidin.

Treatment of warts and molluscum: what does the evidence show?

Strong, high-quality evidence for treatments used very frequently for warts or molluscum is still lacking, but recent publications have helped to strengthen or weaken belief in commonly used therapies and to add weight to the immunological approach to management.

Cantharidin: a comprehensive review of the clinical literature.

Topical cantharidin is a safe and effective treatment for warts, molluscum contagiosum, and callus removal, with promising uses in perforating dermatoses and leishmaniasis.

Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone

Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy, still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment.

Study of Topical Potassium Hydroxide versus Candida Antigen Immunotherapy for Molluscum Contagiosum Management

Evaluated the safety as well as efficacy of intralesional candida Ag immunotherapy versus topical KOH (10 %) in the treatment of Molluscum Contagiosum (MC) and concluded that both topically applied KOH10% and intralucent candida are dependable, less expensive treatments for non-genital MC.

Molluscum Contagiosum, Viral Warts, and Tinea Versicolor

A combination of treatment options is often used for recalcitrant viral warts and molluscum and tinea (pityriasis) versicolor, which usually occurs in adolescents and responds well to treatment with topical antifungal agents.

Topical Cantharidin in the Management of Molluscum Contagiosum: Preliminary Assessment of an Ether-free, Pharmaceutical-grade Formulation.

A recent Phase II pilot study evaluating a specific formulation of cantharidin 0.7% solution [w/v] (VP-102) has demonstrated promising efficacy and safety results, with additional studies forthcoming, including the designated use of a patented application device that contains the solution.

Safe and speedy cantharidin application.

Cantharidin as an Alternative Treatment for Genital Warts: A Case Monitored With Optical Coherence Tomography

A case of a patient with recurrent genital warts (GW), who was treated with cantharidin solution in an individual off-label approach is reported here, based on experience as a reference centre for sexually transmitted diseases.



Childhood molluscum contagiosum: experience with cantharidin therapy in 300 patients.

To the authors' knowledge, this is the largest retrospective series of childhood MC treated with cantharidin, and in these patients the therapy was extremely effective and well tolerated, and parental satisfaction was high.

Cantharidin Use Among Pediatric Dermatologists in the Treatment of Molluscum Contagiosum

Cantharidin is a common modality in the treatment of MC among pediatric dermatologists, and efficacy data is still lacking, but subjective satisfaction with cantharodin is reported.

Childhood molluscum contagiosum

The most current pathophysiology of molluscum contagiosum, a highly contagious viral infection of the mucous membranes and skin, commonly seen in children, is reviewed.

A Prospective Randomized Trial Comparing the Efficacy and Adverse Effects of Four Recognized Treatments of Molluscum Contagiosum in Children

It is believed that the ideal treatment for mollusca depends on the individual patient preference, fear, and financial status, distance from the office, and whether they have dermatitis or blood‐borne infections.

Cantharidin revisited: a blistering defense of an ancient medicine.

Cantharidin is a safe and valuable medication and should be readded to the dermatologic therapeutic armamentarium.

A practical approach to molluscum contagiosum, Part 1: Definition and diagnosis

It's molluscum contagiosum, and while many 'peds' choose to let this infection run its course, there can be benefits to intervention.

Parental Satisfaction, Efficacy, and Adverse Events in 54 Patients Treated With Cantharidin for Molluscum Contagiosum Infection

Cantharidin appears to be equally effective and well-tolerated and should be considered a potential front-line treatment for molluscum contagiosum infection.