Treatment of metastatic breast cancer patients with different dosages of megestrol acetate; dose relations, metabolic and endocrine effects.

@article{AlexievaFigusch1984TreatmentOM,
  title={Treatment of metastatic breast cancer patients with different dosages of megestrol acetate; dose relations, metabolic and endocrine effects.},
  author={J. Alexieva-Figusch and M. Blankenstein and W. Hop and J. Klijn and S. Lamberts and F. de Jong and R. Docter and H. Adlercreutz and H. van Gilse},
  journal={European journal of cancer \& clinical oncology},
  year={1984},
  volume={20 1},
  pages={
          33-40
        }
}
Megestrol acetate (MA) is of therapeutic value in breast cancer patients. This study was designed to evaluate the effects of different dosages of MA on endocrine events potentially influenced by the drug in relation to plasma level of MA and clinical effects in patients with advanced breast cancer. Eighteen postmenopausal patients were randomly distributed over six groups to receive daily 90, 180 or 270 mg of MA (niagestin) orally in a cross-over study consisting of 3 periods of 6 weeks… Expand
Dose-response trial of megestrol acetate in advanced breast cancer: cancer and leukemia group B phase III study 8741.
  • J. Abrams, J. Aisner, +8 authors L. Norton
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 1999
A phase I/II study of high-dose megestrol acetate in the treatment of metastatic breast cancer
Tamoxifen and megestrol acetate for postmenopausal breast cancer
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