Treatment of lymphatic malformations with OK-432 (Picibanil): review of the literature.

@article{Poldervaart2009TreatmentOL,
  title={Treatment of lymphatic malformations with OK-432 (Picibanil): review of the literature.},
  author={Michelle T. Poldervaart and Corstiaan C Breugem and Lucienne A Speleman and Suzanne G. M. A. Pasmans},
  journal={The Journal of craniofacial surgery},
  year={2009},
  volume={20 4},
  pages={1159-62}
}
INTRODUCTION Lymphatic malformations (LM) are benign structural defects that can cause serious complications because of their size and location. Traditionally, surgical removal was the first treatment modality, but this could be associated with many complications and risks. Since Ogita introduced OK-432 (picibanil) in 1987 as a treatment method, this sclerosant has become popular. This paper is a review of the trials published so far on this topic. PATIENTS AND METHODS A literature search of… CONTINUE READING

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