Treatment of knee osteoarthritis with Orthokine-derived autologous conditioned serum.

@article{Fox2010TreatmentOK,
  title={Treatment of knee osteoarthritis with Orthokine-derived autologous conditioned serum.},
  author={Beth Anne Fox and Mary Maniscalco Stephens},
  journal={Expert review of clinical immunology},
  year={2010},
  volume={6 3},
  pages={
          335-45
        }
}
Osteoarthritis (OA) is the most prevalent arthritis in the world with increasing numbers of people expected to acquire the disease as the population ages. Therapies commonly used to manage the disease have limited efficacy and some carry significant risks. Current data suggest that the anti-inflammatory cytokine IL-1 receptor antagonist (IL-1Ra) can alter the inflammatory response and cartilage erosion present in OA. Intra-articular gene expression of IL-1Ra has shown promising results in… CONTINUE READING
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